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Metabolic engineering of Salmonella vaccine bacteria to boost human Vγ2Vδ2 T cell immunity.
Workalemahu G, Wang H, Puan KJ, Nada MH, Kuzuyama T, Jones BD, Jin C, Morita CT. Workalemahu G, et al. J Immunol. 2014 Jul 15;193(2):708-21. doi: 10.4049/jimmunol.1302746. Epub 2014 Jun 18. J Immunol. 2014. PMID: 24943221 Free PMC article.
Whereas microbial infections elicit prolonged expansion of memory Vgamma2Vdelta2 T cells, immunization with prenyl pyrophosphates or aminobisphosphonates elicit short-term Vgamma2Vdelta2 expansion with rapid anergy and deletion upon subsequent immunizations. ...
Whereas microbial infections elicit prolonged expansion of memory Vgamma2Vdelta2 T cells, immunization with prenyl pyrophosphates or aminobi …
Bacterial biofilms: development, dispersal, and therapeutic strategies in the dawn of the postantibiotic era.
Kostakioti M, Hadjifrangiskou M, Hultgren SJ. Kostakioti M, et al. Cold Spring Harb Perspect Med. 2013 Apr 1;3(4):a010306. doi: 10.1101/cshperspect.a010306. Cold Spring Harb Perspect Med. 2013. PMID: 23545571 Free PMC article. Review.
Inside the host, biofilms allow pathogens to subvert innate immune defenses and are thus associated with long-term persistence. Here we provide a general review of the steps leading to biofilm formation on surfaces and within eukaryotic cells, highlighting several medicall …
Inside the host, biofilms allow pathogens to subvert innate immune defenses and are thus associated with long-term persistence. Here …
Towards a safe, effective vaccine for Rift Valley fever virus.
Labeaud D. Labeaud D. Future Virol. 2010 Nov;5(6):675-678. doi: 10.2217/fvl.10.63. Future Virol. 2010. PMID: 21423850 Free PMC article.
Since no therapies currently exist to treat Rift Valley fever, it remains a public and animal health priority to develop safe, effective RVFV vaccines (whether for animals, humans, or both) that provide long-term protective immunity. In the evaluated article, Bhardwaj and …
Since no therapies currently exist to treat Rift Valley fever, it remains a public and animal health priority to develop safe, effective RVF …