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Table representation of search results timeline featuring number of search results per year.

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1993 1
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1997 3
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2010 1
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16 results

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Page 1
Phosphatidylcholine supplementation in pregnant women consuming moderate-choline diets does not enhance infant cognitive function: a randomized, double-blind, placebo-controlled trial.
Cheatham CL, Goldman BD, Fischer LM, da Costa KA, Reznick JS, Zeisel SH. Cheatham CL, et al. Am J Clin Nutr. 2012 Dec;96(6):1465-72. doi: 10.3945/ajcn.112.037184. Epub 2012 Nov 7. Am J Clin Nutr. 2012. PMID: 23134891 Free PMC article. Clinical Trial.
DESIGN: In a double-blind, randomized controlled trial, 140 pregnant women were randomly assigned to receive supplemental phosphatidylcholine (750 mg) or a placebo (corn oil) from 18 wk gestation through 90 d postpartum. Their infants (n = 99) were tested for short-term vi …
DESIGN: In a double-blind, randomized controlled trial, 140 pregnant women were randomly assigned to receive supplemental phosphatidylcholin …
Voluntary running prevents progressive memory decline and increases adult hippocampal neurogenesis and growth factor expression after whole-brain irradiation.
Wong-Goodrich SJ, Pfau ML, Flores CT, Fraser JA, Williams CL, Jones LW. Wong-Goodrich SJ, et al. Cancer Res. 2010 Nov 15;70(22):9329-38. doi: 10.1158/0008-5472.CAN-10-1854. Epub 2010 Sep 30. Cancer Res. 2010. PMID: 20884629 Free PMC article.
Previous studies using animal models to address this issue have yielded mixed results and have not examined potential molecular mechanisms. We investigated the short- and long-term effects of WBI on spatial learning and memory retention and determined whether voluntary run …
Previous studies using animal models to address this issue have yielded mixed results and have not examined potential molecular mechanisms. …
Gene response elements, genetic polymorphisms and epigenetics influence the human dietary requirement for choline.
Zeisel SH. Zeisel SH. IUBMB Life. 2007 Jun;59(6):380-7. doi: 10.1080/15216540701468954. IUBMB Life. 2007. PMID: 17613168 Free PMC article. Review.
Choline is critical during fetal development, when it alters DNA methylation and thereby influences neural precursor cell proliferation and apoptosis. This results in long term alterations in brain structure and function, specifically memory function....
Choline is critical during fetal development, when it alters DNA methylation and thereby influences neural precursor cell proliferation and …
Dietary prenatal choline supplementation alters postnatal hippocampal structure and function.
Li Q, Guo-Ross S, Lewis DV, Turner D, White AM, Wilson WA, Swartzwelder HS. Li Q, et al. J Neurophysiol. 2004 Apr;91(4):1545-55. doi: 10.1152/jn.00785.2003. Epub 2003 Nov 26. J Neurophysiol. 2004. PMID: 14645379 Free article.
Specifically, prenatal choline supplementation has been shown to enhance working memory and hippocampal long-term potentiation (LTP) in adult offspring. However, the cellular mechanisms underlying these effects remain unclear. ...
Specifically, prenatal choline supplementation has been shown to enhance working memory and hippocampal long-term potentiation (LTP) …
Choline availability to the developing rat fetus alters adult hippocampal long-term potentiation.
Jones JP, Meck WH, Williams CL, Wilson WA, Swartzwelder HS. Jones JP, et al. Brain Res Dev Brain Res. 1999 Dec 10;118(1-2):159-67. doi: 10.1016/s0165-3806(99)00103-0. Brain Res Dev Brain Res. 1999. PMID: 10611515
To determine if the behavioral effects of choline are related to physiological changes in hippocampus, the effect of perinatal choline supplementation or deficiency on long-term potentiation (LTP) was examined in hippocampal slices of 6-8 and 12-14 month old rats born to d …
To determine if the behavioral effects of choline are related to physiological changes in hippocampus, the effect of perinatal choline suppl …
Prenatal availability of choline alters the development of acetylcholinesterase in the rat hippocampus.
Cermak JM, Blusztajn JK, Meck WH, Williams CL, Fitzgerald CM, Rosene DL, Loy R. Cermak JM, et al. Dev Neurosci. 1999;21(2):94-104. doi: 10.1159/000017371. Dev Neurosci. 1999. PMID: 10449981
In addition, the prenatal Ch availability was found to alter the size and density of AChE-positive PD20 interneurons. These results show that prenatal Ch availability has long-term consequences on the development of the hippocampal cholinergic system....
In addition, the prenatal Ch availability was found to alter the size and density of AChE-positive PD20 interneurons. These results show tha …
Granule cells in aging rats are sexually dimorphic in their response to estradiol.
Miranda P, Williams CL, Einstein G. Miranda P, et al. J Neurosci. 1999 May 1;19(9):3316-25. doi: 10.1523/JNEUROSCI.19-09-03316.1999. J Neurosci. 1999. PMID: 10212291 Free PMC article.
We found the following: (1) Aged female dentate granule cells deprived of gonadal steroids long-term have a paucity of dendritic spines compared with young females deprived short-term; however, aged male dentate granule cells deprived of gonadal steroids long-ter …
We found the following: (1) Aged female dentate granule cells deprived of gonadal steroids long-term have a paucity of dendritic spin …
Choline deficiency induces apoptosis and decreases the number of eosinophilic preneoplastic foci in the liver of OXYS rats.
Albright CD, Zeisel SH, Salganik RI. Albright CD, et al. Pathobiology. 1998;66(2):71-6. doi: 10.1159/000027999. Pathobiology. 1998. PMID: 9645630
Choline deficiency (CD) was previously shown to trigger apoptosis in rat hepatocytes in culture and in vivo. In the present study we investigated the effects of short-term withdrawal of choline from the diet on the expression of putative preneoplastic foci in OXYS rats, an …
Choline deficiency (CD) was previously shown to trigger apoptosis in rat hepatocytes in culture and in vivo. In the present study we investi …
Choline availability modulates the expression of TGFbeta1 and cytoskeletal proteins in the hippocampus of developing rat brain.
Albright CD, Tsai AY, Mar MH, Zeisel SH. Albright CD, et al. Neurochem Res. 1998 May;23(5):751-8. doi: 10.1023/a:1022411510636. Neurochem Res. 1998. PMID: 9566615
Choline availability influences long-term memory in concert with changes in the spatial organization and morphology of septal neurons, however little is known concerning the effects of choline on the hippocampus, a region of the brain also important for memory performance. …
Choline availability influences long-term memory in concert with changes in the spatial organization and morphology of septal neurons …
16 results