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Coexistence of two forms of LTP in ACC provides a synaptic mechanism for the interactions between anxiety and chronic pain.
Koga K, Descalzi G, Chen T, Ko HG, Lu J, Li S, Son J, Kim T, Kwak C, Huganir RL, Zhao MG, Kaang BK, Collingridge GL, Zhuo M. Koga K, et al. Neuron. 2015 Jan 21;85(2):377-89. doi: 10.1016/j.neuron.2014.12.021. Epub 2014 Dec 31. Neuron. 2015. PMID: 25556835 Free PMC article.
Unfortunately, little is known about the synaptic mechanisms that mediate these re-enforcing interactions. Here we characterized two forms of long-term potentiation (LTP) in the anterior cingulate cortex (ACC); a presynaptic form (pre-LTP) that requires kainate receptors a …
Unfortunately, little is known about the synaptic mechanisms that mediate these re-enforcing interactions. Here we characterized two forms o …
Erasing injury-related cortical synaptic potentiation as a new treatment for chronic pain.
Li XY, Ko HG, Chen T, Collingridge GL, Kaang BK, Zhuo M. Li XY, et al. J Mol Med (Berl). 2011 Sep;89(9):847-55. doi: 10.1007/s00109-011-0768-9. Epub 2011 May 17. J Mol Med (Berl). 2011. PMID: 21584648 Review.
The investigation of molecular mechanism responsible for maintaining injury-related plastic changes, such as through the study of long-term potentiation in these structures, provides potential novel targets for designing new medicine for chronic pain. ...
The investigation of molecular mechanism responsible for maintaining injury-related plastic changes, such as through the study of long-te …
Sleep deprivation impairs cAMP signalling in the hippocampus.
Vecsey CG, Baillie GS, Jaganath D, Havekes R, Daniels A, Wimmer M, Huang T, Brown KM, Li XY, Descalzi G, Kim SS, Chen T, Shang YZ, Zhuo M, Houslay MD, Abel T. Vecsey CG, et al. Nature. 2009 Oct 22;461(7267):1122-5. doi: 10.1038/nature08488. Nature. 2009. PMID: 19847264 Free PMC article.