Whole-grain and fiber intakes and periodontitis risk in men

Am J Clin Nutr. 2006 Jun;83(6):1395-400. doi: 10.1093/ajcn/83.6.1395.

Abstract

Background: Diabetes and hyperglycemia increase periodontitis risk, severity, and extent. Increased whole-grain and fiber intakes are associated with improved insulin sensitivity and may therefore affect periodontitis risk.

Objective: The objective was to examine the associations between whole-grain and fiber intakes and periodontitis risk.

Design: We prospectively followed 34,160 male US health professionals aged 40-75 y at the outset. We updated medical and lifestyle information biennially with questionnaires and diet every 4 y by using a validated food-frequency questionnaire. We excluded men reporting periodontitis, myocardial infarction, stroke, and hypercholesterolemia before 1986 and those with incomplete dietary data. All diabetics were excluded. Periodontitis was determined by a report of professionally diagnosed disease and validated by a diagnosis of periodontitis by a periodontist from a blinded review of radiographs.

Results: Men in the highest quintile of whole-grain intake were 23% less likely to get periodontitis than were those in the lowest quintile (multivariate RR: 0.77; 95% CI: 0.66, 0.89; P for trend < 0.001) after adjustment for age, smoking, body mass index, alcohol intake, physical activity, and total energy intake. Periodontitis was not associated with refined-grain intake (multivariate RR comparing extreme quintiles of intake: 1.04; 95% CI: 0.89, 1.23; P for trend = 0.37). Cereal fiber was inversely related to periodontitis risk (multivariate RR comparing extreme quintiles of intake: 0.85; 95% CI: 0.73, 0.99; P for trend = 0.03), but the association was not significant after adjustment for whole-grain intake.

Conclusion: Increasing whole grain in the diet without increasing total energy intake may reduce periodontitis risk.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Aged
  • Diet / statistics & numerical data*
  • Diet Surveys
  • Dietary Fiber / administration & dosage
  • Dietary Fiber / therapeutic use*
  • Edible Grain*
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Periodontitis / prevention & control*
  • Risk Factors