Seven Achilles tendinitis including 3 complicated by rupture during fluoroquinolone therapy

J Rheumatol. 1992 Sep;19(9):1479-81.

Abstract

We describe 7 Achilles tendinitis occurring during fluoroquinolone treatment. Antibiotic agents used were pefloxacin and ofloxacin. In 3 cases the course was complicated by rupture of the tendon, one of which is histologically documented. The toxic effects of quinolones on tendon is discussed.

MeSH terms

  • Achilles Tendon / injuries*
  • Achilles Tendon / pathology*
  • Aged
  • Aged, 80 and over
  • Anti-Infective Agents / adverse effects*
  • Anti-Infective Agents / therapeutic use
  • Bronchitis / drug therapy
  • Cystitis / drug therapy
  • Female
  • Humans
  • Male
  • Middle Aged
  • Ofloxacin / therapeutic use
  • Pefloxacin / therapeutic use
  • Rupture, Spontaneous / chemically induced
  • Spondylitis / drug therapy
  • Tendinopathy / complications*
  • Tendinopathy / pathology
  • Tendon Injuries / complications*

Substances

  • Anti-Infective Agents
  • Pefloxacin
  • Ofloxacin