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Page 1
N-Acetylcysteine: A Review of Clinical Usefulness (an Old Drug with New Tricks).
Schwalfenberg GK. Schwalfenberg GK. J Nutr Metab. 2021 Jun 9;2021:9949453. doi: 10.1155/2021/9949453. eCollection 2021. J Nutr Metab. 2021. PMID: 34221501 Free PMC article. Review.
N-acetylcysteine may be useful as an adjuvant in treating various medical conditions, especially chronic diseases. These conditions include polycystic ovary disease, male infertility, sleep apnea, acquired immune deficiency syndrome, influenza, parkinsonism, multiple scler …
N-acetylcysteine may be useful as an adjuvant in treating various medical conditions, especially chronic diseases. These conditions include …
Suppression of uterine and placental ferroptosis by N-acetylcysteine in a rat model of polycystic ovary syndrome.
Hu M, Zhang Y, Ma S, Li J, Wang X, Liang M, Sferruzzi-Perri AN, Wu X, Ma H, Brännström M, Shao LR, Billig H. Hu M, et al. Mol Hum Reprod. 2021 Nov 27;27(12):gaab067. doi: 10.1093/molehr/gaab067. Mol Hum Reprod. 2021. PMID: 34850077
The mechanisms that link hyperandrogenism and insulin (INS) resistance (HAIR) to the increased miscarriage rate in women with polycystic ovary syndrome (PCOS) remain elusive. Previous studies demonstrate that increased uterine and placental ferroptosis is associated …
The mechanisms that link hyperandrogenism and insulin (INS) resistance (HAIR) to the increased miscarriage rate in women with polycystic …
N-acetyl-cysteine as adjuvant therapy in female infertility: a systematic review and meta-analysis.
Devi N, Boya C, Chhabra M, Bansal D. Devi N, et al. J Basic Clin Physiol Pharmacol. 2020 Nov 19;32(5):899-910. doi: 10.1515/jbcpp-2020-0107. J Basic Clin Physiol Pharmacol. 2020. PMID: 34592079 Review.
Overall, NAC showed statistically insignificant (OR=0.98-2.47). OUTLOOK: NAC can be an effective adjuvant in PCOS related and unexplained female infertility. The effect could be more profound in women with high BMI, insulin resistance, and oxidative stress. ...
Overall, NAC showed statistically insignificant (OR=0.98-2.47). OUTLOOK: NAC can be an effective adjuvant in PCOS related and unexpla …
N-acetylcysteine for polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled clinical trials.
Thakker D, Raval A, Patel I, Walia R. Thakker D, et al. Obstet Gynecol Int. 2015;2015:817849. doi: 10.1155/2015/817849. Epub 2015 Jan 8. Obstet Gynecol Int. 2015. PMID: 25653680 Free PMC article. Review.
To review the benefits and harms of N-acetylcysteine (NAC) in women with polycystic ovary syndrome (PCOS). Method. Literature search was conducted using the bibliographic databases, MEDLINE (Ovid), CINAHL, EMBASE, Scopus, PsyInfo, and PROQUEST (from inception to Sep …
To review the benefits and harms of N-acetylcysteine (NAC) in women with polycystic ovary syndrome (PCOS). Method. Literature …
Comparison of the efficacy between NAC and metformin in treating PCOS patients: a meta-analysis.
Song Y, Wang H, Huang H, Zhu Z. Song Y, et al. Gynecol Endocrinol. 2020 Mar;36(3):204-210. doi: 10.1080/09513590.2019.1689553. Epub 2019 Nov 21. Gynecol Endocrinol. 2020. PMID: 31749393
Our aim is to evaluate the clinical effectiveness and safety by comparing N-acetyl-cysteine (NAC) with metformin administrated by polycystic ovary syndrome (PCOS) patients. Systematic review and meta-analysis of randomized clinical trials (RCTs). ...In conclusions, …
Our aim is to evaluate the clinical effectiveness and safety by comparing N-acetyl-cysteine (NAC) with metformin administrated by polycys …
Effects of N-acetylcysteine and metformin treatment on the stereopathological characteristics of uterus and ovary.
Rafiee B, Karbalay-Doust S, Tabei SMB, Azarpira N, Alaee S, Lohrasbi P, Bahmanpour S. Rafiee B, et al. Eur J Transl Myol. 2022 May 9;32(2):10409. doi: 10.4081/ejtm.2022.10409. Eur J Transl Myol. 2022. PMID: 35535444 Free PMC article.
In this study, the stereo-pathological effect of metformin and N-acetyl cysteine is evaluated on the uterus and ovary of polycystic ovary syndrome (PCOS) mice. 96 mature females (8-weekold, weight of 20-30 gr) BALB/c mice were classified into 6 groups including the …
In this study, the stereo-pathological effect of metformin and N-acetyl cysteine is evaluated on the uterus and ovary of polycystic o …
Oxidative Stress in Polycystic Ovarian Syndrome and the Effect of Antioxidant N-Acetylcysteine on Ovulation and Pregnancy Rate.
Sandhu JK, Waqar A, Jain A, Joseph C, Srivastava K, Ochuba O, Alkayyali T, Ruo SW, Poudel S. Sandhu JK, et al. Cureus. 2021 Sep 11;13(9):e17887. doi: 10.7759/cureus.17887. eCollection 2021 Sep. Cureus. 2021. PMID: 34660086 Free PMC article. Review.
Polycystic ovarian syndrome (PCOS) is an endocrinological condition that leads to infertility in many females. N-acetylcysteine (NAC), a novel antioxidant, is being used as an adjuvant to treat infertility in females suffering from PCOS. This review aims to e …
Polycystic ovarian syndrome (PCOS) is an endocrinological condition that leads to infertility in many females. N-acetylcystein …
Clinical, endocrine and metabolic effects of metformin vs N-acetyl-cysteine in women with polycystic ovary syndrome.
Oner G, Muderris II. Oner G, et al. Eur J Obstet Gynecol Reprod Biol. 2011 Nov;159(1):127-31. doi: 10.1016/j.ejogrb.2011.07.005. Epub 2011 Aug 9. Eur J Obstet Gynecol Reprod Biol. 2011. PMID: 21831508 Clinical Trial.
OBJECTIVE: To evaluate the clinical, endocrine and metabolic effects of metformin and N-acetyl-cysteine (NAC) in patients with polycystic ovary syndrome (PCOS). STUDY DESIGN: In this prospective trial, 100 women with PCOS were randomly divided to receive metf …
OBJECTIVE: To evaluate the clinical, endocrine and metabolic effects of metformin and N-acetyl-cysteine (NAC) in patients with polycystic …
Comparison of metformin and N-acetyl cysteine, as an adjuvant to clomiphene citrate, in clomiphene-resistant women with polycystic ovary syndrome.
Nemati M, Nemati S, Taheri AM, Heidari B. Nemati M, et al. J Gynecol Obstet Hum Reprod. 2017 Sep;46(7):579-585. doi: 10.1016/j.jogoh.2017.07.004. Epub 2017 Jul 8. J Gynecol Obstet Hum Reprod. 2017. PMID: 28698075 Clinical Trial.
OBJECTIVE: To evaluate the effects of short- and long-term treatment with metformin and NAC, in an adjuvant to clomiphene citrate (CC), on the improvement of hormonal profile (SHBG, total testosterone, FBS, and fasting insulin) and fertility status in CC-resistant women with P …
OBJECTIVE: To evaluate the effects of short- and long-term treatment with metformin and NAC, in an adjuvant to clomiphene citrate (CC), on t …
N-Acetyl cysteine and clomiphene citrate for induction of ovulation in polycystic ovary syndrome: a cross-over trial.
Badawy A, State O, Abdelgawad S. Badawy A, et al. Acta Obstet Gynecol Scand. 2007;86(2):218-22. doi: 10.1080/00016340601090337. Acta Obstet Gynecol Scand. 2007. PMID: 17364286 Free article. Clinical Trial.
OBJECTIVE: To compare clomiphene citrate plus N-acetyl cysteine versus clomiphene citrate for inducing ovulation in patients with polycystic ovary syndrome. DESIGN: Prospective cross-over trial. SETTING: University teaching hospital and a private practice setting. ...CONCL …
OBJECTIVE: To compare clomiphene citrate plus N-acetyl cysteine versus clomiphene citrate for inducing ovulation in patients with polycys …
38 results